Maciej Lech Selected Research

IRS 954

6/2007

Inhibition of Toll-like receptor-7 (TLR-7) or TLR-7 plus TLR-9 attenuates glomerulonephritis and lung injury in experimental lupus.

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Maciej Lech Research Topics

Disease

17	Inflammation (Inflammations) 01/2022 - 04/2013
10	Lupus Nephritis 01/2018 - 12/2006
7	Fibrosis (Cirrhosis) 01/2019 - 04/2011
6	Necrosis 12/2016 - 08/2010
5	Reperfusion Injury 01/2022 - 01/2012
5	Glomerulonephritis 09/2020 - 11/2006
5	Acute Kidney Injury (Acute Renal Failure) 08/2013 - 09/2009
4	Autoimmune Diseases (Autoimmune Disease) 01/2022 - 03/2010
4	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2018 - 12/2006
4	Chronic Renal Insufficiency 01/2018 - 04/2011
3	Nephritis 01/2021 - 09/2020
2	Proteinuria 09/2020 - 12/2006
2	Kidney Calculi (Kidney Stone) 01/2018 - 03/2017
2	Nephrocalcinosis 01/2018 - 03/2017
2	Bacterial Infections (Bacterial Infection) 01/2017 - 01/2016
2	Atrophy 02/2014 - 04/2011
2	Kidney Diseases (Kidney Disease) 08/2013 - 04/2013
2	Infections 12/2011 - 11/2006
2	Immune Complex Diseases (Immune Complex Disease) 08/2011 - 08/2007
1	Rheumatoid Arthritis 01/2022
1	Cytokine Release Syndrome 01/2021
1	Pneumonia (Pneumonitis) 01/2021
1	Hyperuricemia 12/2020
1	B-Cell Lymphoma (Lymphoma, B Cell) 01/2020
1	Chronic Kidney Failure (Chronic Renal Failure) 01/2018
1	Body Weight (Weight, Body) 01/2018
1	Pathologic Processes 01/2018
1	Primary Hyperoxaluria (Oxaluria, Primary) 03/2017
1	Hyperoxaluria (Oxaluria) 03/2017
1	Periodontitis 01/2017
1	Bone Resorption 01/2017
1	Porcine Reproductive and Respiratory Syndrome (PRRS) 09/2013
1	Autoimmune Pancreatitis 11/2012
1	Pancreatitis 11/2012
1	Ureteral Obstruction 04/2011

Drug/Important Bio-Agent (IBA)

8	CytokinesIBA 01/2021 - 08/2010
8	Toll-Like Receptors (Toll-Like Receptor)IBA 12/2017 - 11/2006
7	Messenger RNA (mRNA)IBA 01/2017 - 09/2009
6	Interleukin-6 (Interleukin 6)IBA 01/2017 - 08/2007
5	Proteins (Proteins, Gene)FDA Link 01/2022 - 09/2009
4	Immunoglobulin G (IgG)IBA 01/2021 - 12/2006
4	Antigen-Antibody Complex (Immune Complex)IBA 12/2017 - 11/2006
3	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2022 - 01/2018
3	AutoantibodiesIBA 11/2012 - 12/2006
2	Chemotactic FactorsIBA 01/2021 - 01/2016
2	Transcription Factors (Transcription Factor)IBA 01/2021 - 01/2020
2	Uric Acid (Urate)IBA 12/2020 - 03/2014
2	aristolochic acid I (aristolochic acid)IBA 12/2020 - 01/2018
2	Calcium OxalateIBA 01/2018 - 03/2017
2	ChemokinesIBA 01/2018 - 04/2011
2	LigandsIBA 12/2017 - 12/2006
2	Type I Tumor Necrosis Factor ReceptorsIBA 03/2017 - 12/2016
2	Lymphotoxin-alpha (Lymphotoxin)IBA 01/2016 - 11/2012
2	DNA (Deoxyribonucleic Acid)IBA 02/2014 - 12/2006
2	Etanercept (Enbrel)FDA Link 02/2014 - 08/2010
2	Pattern Recognition ReceptorsIBA 09/2013 - 08/2013
2	Clodronic Acid (Clodronate)IBA 08/2010 - 09/2009
2	Imiquimod (Aldara)FDA LinkGeneric 08/2007 - 12/2006
2	RNA (Ribonucleic Acid)IBA 08/2007 - 12/2006
1	Monocyte Chemoattractant ProteinsIBA 01/2022
1	EndonucleasesIBA 01/2021
1	Adenosine (Adenocard)FDA LinkGeneric 12/2020
1	antiglomerular basement membrane antibodyIBA 09/2020
1	Growth Differentiation Factor 15IBA 09/2020
1	Interferon Regulatory FactorsIBA 01/2019
1	MicroRNAs (MicroRNA)IBA 01/2018
1	Therapeutic UsesIBA 01/2018
1	Folic Acid (Vitamin M)FDA LinkGeneric 01/2018
1	Cisplatin (Platino)FDA LinkGeneric 01/2018
1	SilverIBA 01/2018
1	Biological ProductsIBA 01/2018
1	Interleukin-22 (IL-22)IBA 12/2017
1	OxalatesIBA 03/2017
1	Annexin A2 (Annexin II)IBA 03/2017
1	R-7050IBA 03/2017
1	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 03/2017
1	Type II Tumor Necrosis Factor ReceptorsIBA 03/2017
1	Gingipain Cysteine EndopeptidasesIBA 01/2017
1	Cyclophilins (Cyclophilin)IBA 12/2016
1	Protein Kinases (Protein Kinase)IBA 12/2016
1	Phosphotransferases (Kinase)IBA 12/2016
1	Inhibitor of Apoptosis ProteinsIBA 12/2016
1	Poly (ADP-Ribose) Polymerase-1IBA 12/2016
1	Glutathione (Reduced Glutathione)IBA 12/2016
1	Interleukin-8 (Interleukin 8)IBA 01/2016
1	Interleukin-18 (Interleukin 18)IBA 12/2015
1	LymphokinesIBA 12/2015
1	AutoantigensIBA 09/2013
1	InflammasomesIBA 08/2013
1	InterleukinsIBA 04/2013
1	C-Reactive ProteinIBA 04/2013
1	Biomarkers (Surrogate Marker)IBA 04/2013
1	Amyloid (Amyloid Fibrils)IBA 04/2013
1	PTX3 proteinIBA 04/2013
1	Trypsin InhibitorsIBA 11/2012
1	Adrenal Cortex Hormones (Corticosteroids)IBA 11/2012
1	dectin 1IBA 01/2012
1	DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN)IBA 01/2012
1	Interleukin-1 Receptor-Associated KinasesIBA 12/2011
1	Complement System Proteins (Complement)IBA 08/2011